ETP-47799 - CDK8/19i

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3525

CAS [923596-52-5]

MF C14H15N5
MW 253.30

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH

ETP-47799

Description

ETP-47799 is a potent CDK8/19 inhibitor with IC50 values of 2.9 nM and 14.1 nM for CDK8 and CDK19, respectively. ETP-47799 stimulates Mediator recruitment of RNA Pol II. This effectively hyper-activates enhancers and stabilizes the transcriptional program of naïve pluripotent cell identity.

Keywords: ETP-47799 | Supplier | CDK8/CDK19 inhibitor | CDK8/19i | ETP47799 | ETP 47799 | CAS [923596-52-5] | DNA-RNA | CDK | Inhibitor | Enzymes | Pluripotent stem cells | PSC

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5 mg €90.00 In Stock
25 mg €310.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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