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Diethylcarbamazine citrate
- Hetrazan - DEC- Parent CAS: 90-89-1
- Soluble in water and DMSO
- MF: C10H21N3O.C6H8O7
- MW: 391.42
Description
Diethylcarbamazine citrate (DEC) is a filaricidal drug. Pharmacological studies showed that DEC interferes with arachidonic acid metabolism, acting as an anti-inflammatory drug. It has been found that DEC blocks a number of steps in both the cyclooxygenase (COX) and lipoxygenase pathways, including the inhibition of leucocyte chemotaxis, granulocyte degranulation, and peripheral vasodilation.
More Information
| Parent CAS No. | 90-89-1 |
|---|---|
| Chemical Name | N,N-Diethyl-4-methylpiperazine-1-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate |
| SMILES | N1(C)CCN(C(=O)N(CC)CC)CC1.OC(=O)CC(C(=O)O)(O)CC(=O)O |
| MFCD | MFCD00039124 |
| InChi | InChI=1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12) |
| InChiKey | PGNKBEARDDELNB-UHFFFAOYSA-N |
| CID | 15432 |
| Short Description | Filaricidal drug |
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