Bulk Inquiry
ML 351
Axon 2312
CAS:
847163-28-4
Purity:
98%
- Soluble in DMSO
- MF: C15H11N3O
- MW: 249.27
Description
Potent and selective inhibitor of 12/15-lipoxygenase (IC50 value 200 nM against human 12/15-LOX) with >250-fold selectivity versus related LOX isozymes. ML351 is protective against oxidative glutamate toxicity in mouse neuronal HT22 cells and does not reduce the active-site ferric ion. ML 351 significantly reduced infarct size following permanent focal ischemia in a mouse model of ischemic stroke
More Information
| Parent CAS No. | 847163-28-4 |
|---|---|
| Chemical Name | 5-(methylamino)-2-(naphthalen-1-yl)oxazole-4-carbonitrile |
| SMILES | O1C(NC)=C(C#N)N=C1C1=C2C(C=CC=C2)=CC=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3 |
| InChiKey | DYXYXTDIFMDJIR-UHFFFAOYSA-N |
| CID | 664510 |
| Short Description | Lipoxygenase inhibitor |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1919 | Celecoxib |
From $55.00 |
| 1974 | GW 406381 |
From $132.00 |
| 2106 | Valdecoxib |
From $88.00 |
| 2108 | SC 236 |
From $88.00 |
| 2112 | SC 26196 |
From $93.50 |
| 2288 | ATB 346 |
From $121.00 |
| 2844 | ThioLox |
From $132.00 |
| 2873 | ML 355 |
From $104.50 |
| 2989 | 15-LOX-1 inhibitor i472 |
From $187.00 |
| 3176 | Diethylcarbamazine citrate |
From $55.00 |
| 3256 | Zileuton |
From $55.00 |
Other Categories
Get a Quote for
Loading...