UNC 9994 hydrochloride

Based on 38 reference(s) in Google Scholar 9 10 38

Axon 2562

CAS [N.A.]

MF C21H22Cl2N2OS.HCl
MW 457.84

  • Purity: 99%
  • Soluble in DMSO

UNC 9994 hydrochloride

Description

Unique, β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in β-arrestin-2 knockout mice.

KEYWORDS: UNC 9994 hydrochloride | supplier | D2 agonist | Axon Medchem | Axon 2562 | UNC9994 | CAS [1354030-51-5] | Dopamine | D2 | Agonist | GPCR | D2R | β-arrestin | beta-arrestin | antipsychotic

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Size Unit Price Stock
2 mg €120.00 In Stock
5 mg €180.00 In Stock
25 mg €680.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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