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Axon 2520
CAS [109511-58-2]
MF C18H16N6S2MW 380.49
Non-competitive inhibitior of the dual specificity kinase MEK (IC50 values 0.07 μM and 0.06 μM for MEK1 and MEK2, respectively) that protects the brain against damage resulting from ischemic stroke in mice. U0126 is frequently used in combination with PD 98059 (Axon 1223), and both are found to accelerate differentiation of murine RAW264.7 cells into osteoclast-like cells.
KEYWORDS: U 0126 | Supplier | MEK1/2 inhibitor | U 126 | U0126 | U126 | CAS [109511-58-2] | [1173097-76-1] | MAPK | MEK | Inhibitor | Ischemia | stroke | differentiation | osteoclast-like cells
2,3-bis(amino(2-aminophenylthio)methylene)succinonitrile
[109511-58-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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