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PD98059
- NSC 679828
- Soluble in DMSO
- MF: C16H13NO3
- MW: 267.28
Description
More Information
| Parent CAS No. | 167869-21-8 |
|---|---|
| Chemical Name | 2-(2-Amino-3-methoxy-phenyl)-chromen-4-one |
| SMILES | C1C=C2C(=O)C=C(C3C(N)=C(OC)C=CC=3)OC2=CC=1 |
| MFCD | MFCD00671789 |
| InChi | InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3 |
| InChiKey | QFWCYNPOPKQOKV-UHFFFAOYSA-N |
| CID | 4713 |
| Short Description | MEK inhibitor |
References
- DR Alessi et al. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 1995, 270(46), 27489-94.
- FJ Dumont et al. Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production. J. Immunol. 1998, 160(6), 2579-89.
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