Santacruzamate A - CAY 10683

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2495

CAS [1477949-42-0]

MF C15H22N2O3
MW 278.35

  • Purity: 99%
  • Soluble in DMSO

Santacruzamate A


Picomolar level Class I HDAC2 inhibitor (IC50 value 0.11 nM) with relatively little inhibition of HDAC4 or HDAC6 (IC50 values >1000 nM and 433 nM, respectively). Cytotoxin with several structural features in common with Vorinostat, a clinically approved HDAC inhibitor used to treat refractory cutaneous T-cell lymphoma.

Note: Potency of synthetic Santacruzamate A is questioned due to lack of cytotoxicity tested in two cancer cell lines (Q. Liu et al. 2015)

Size Unit Price Stock
10 mg €85.00 In Stock
50 mg €255.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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