Nexturastat A

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2359

CAS [1403783-31-2]

MF C19H23N3O3
MW 341.40

  • Purity: 99%
  • Soluble in DMSO

Nexturastat A

Description

Potent HDAC6 inhibitor with >600 fold and >190 fold selectivity over HDAC1 and HDAC8, respectively (IC50 values 5 nM, 3 µM, 1 µM for HDAC6, HDAC1, and HDAC8, respectively). Nexturastat A was found to be capable of increasing acetylated α-tubulin levels and it inhibited the growth of B16 melanoma cells, albeit with lower potency than LBH 589 (Axon 1548).

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €325.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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