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NNC 756

Name: NNC 756
SKU: 1405

- Odapipam

Axon 1405

CAS: 131796-63-9

Optical Purity: 99% e.e.

Soluble in DMSO

MF: C19H20ClNO2
MW: 329.82

Description

Selective and very potent D1 antagonist; more potent than SCH23390.

More Information

Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	131796-63-9
Chemical Name	(S)-(+)-8-Chloro-5-(2,3-dihydro-benzofuran-7-yl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
SMILES	[C@@H]1(C2C3OCCC=3C=CC=2)C2C=C(O)C(Cl)=CC=2CCN(C)C1 \|&1:0,r\|
MFCD	N.A.
InChi	InChI=1S/C19H20ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3/t16-/m1/s1
InChiKey	SKMVRXPBCSTNKE-MRXNPFEDSA-N
CID	132421
Short Description	D1 antagonist

NNC 756 CAS 131796-63-9 CAS 131796-63-9 Axon 1405 D1 antagonist Axon Ligands Axon Medchem Supplier Odapipam Axon1405 NNC756 Odapipam D1 Vendor

References

EB Nielsen, PH Andersen. Dopamine receptor occupancy in vivo: behavioral correlates using NNC-112, NNC-687 and NNC-756, new selective dopamine D1 receptor antagonists. Eur. J. Pharmacol. 1992, 219(1), 35-44; ibid 45-52.
A Abi-Dargham et al. PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756. Synapse. 1999, 32(2), 93-109.

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NNC 756

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