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(±)-PD128907 hydrochloride
- PD125530
Axon 1072
- Parent CAS: 123594-64-9
Purity:
99%
- Soluble in DMSO
- MF: C14H19NO3.HCl
- MW: 285.77
Description
(±)-PD128907 hydrochloride is the racemic form of PD128907, a selective dopamine D3 receptor agonist. It is used to activate D3 receptor-mediated signaling and to compare racemic activity with the trans-(+)- and (-)-enantiomers.
D3 receptors participate in mesolimbic dopamine signaling, reward biology and neuropsychiatric pathway research. (±)-PD128907 hydrochloride is suited for D3 receptor activation assays and stereochemical structure-activity comparisons.
Key Features
- Selective dopamine D3 receptor agonist
- Racemic PD128907 reference compound
- Activates D3 receptor-mediated GPCR signaling
- Useful for comparison with enantiopure PD128907 analogues
Applications
- Dopamine D3 receptor pharmacology
- Mesolimbic dopamine signaling studies
- Stereoselective agonist activity comparison
- CNS receptor functional assays
More Information
| Parent CAS No. | 123594-64-9 |
|---|---|
| Chemical Name | trans-(+/-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol hydrochloride |
| MFCD | MFCD01529976 |
| Short Description | D3 agonist |
References
- Pugsley et al. Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907. J. Pharmacol. Exp. Ther. 1995, 275 1355.
- G.N. Bancroft et al. Binding of [3H]PD 128907, a Putatively Selective Ligand for the D3 Dopamine Receptor, in Rat Brain: A Receptor Binding and Quantitative Autoradiographic Study. Neuropsychopharmacol. 1998, 18, 305-316.
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