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Naive Stem Cell NHSM inhibitor Set
- Stem Cell 6i inhibitor Set
Set of 6 Inhibitors
CHIR99021 (Axon 1386)
PD0325901 (Axon 1408)
BIRB 796 (Axon 1358)
SP 600125 (Axon 2519)
Gö 6983 (Axon 2466)
Y 27632 dihydrochloride (Axon 1683)
(2 mg or 5 mg of each inhibitor)
* Six Inhibitors are in powder form (high purity: 99%).
Ready to be reconstituted freshly to their 10 mM solutions in DMSO respectively.
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Description
A convenient set of six small molecule pathway inhibitors (termed as Naive stem cell 6i or NHSM inhibitors): - GSK3 inhibitor CHIR99021 (Axon 1386) - MEK inhibitor PD 0325901 (Axon 1408) - p38 inhibitor BIRB 796 (Axon 1358) - JNK inhibitor SP 600125 (Axon 2519) - PKC inhibitor Gö 6983 (Axon 2466) - ROCK inhibitor Y 27632 dihydrochloride (Axon 1683) These 6 small molecule inhibitors were used in the basic NHSM composition as published in Gafni et al. Nature 2013 and with modifications at Hanna lab, the Weizmann Institute of Science (WIS). Useful tool for isolation, generation, derivatization and stabilization of naive human pluripotent stem cells.
Read more: Additional Product Information
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More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | N.A. |
| MFCD | N.A. |
| Short Description | Stem cell inhibitor set |
References
- O. Gafni et al. Derivation of novel human ground state naive pluripotent stem cells. Nature. 2013 Dec 12;504(7479):282-6.
- Hanna Lab, WIS-NHSM human naive medium formulation & protocols
- List of publications using PD0325901 (Axon 1408) purchased from Axon Medchem
- List of publications using CHIR99021 (Axon 1386) purchased from Axon Medchem
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