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Stem Cell 3i inhibitor Set
Set of 3 Inhibitors
SU5402 (Axon 1667)
PD184352 (Axon 1368)
CHIR99021 (Axon 1386)
(2 mg or 5 mg of each inhibitor)
* Three Inhibitors are in powder form (high purity: 99%)
Ready to be reconstituted freshly
to their 10 mM solutions in DMSO respectively.
Expert Recommendation!
Description
A convenient set of FGFR inhibitor SU5402 (Axon 1667), MEK inhibitor PD184352 (Axon 1368) and GSK-3 inhibitor CHIR99021 (Axon 1386); This conventional 3i inhibitor set, used together to sustain mouse embryonic stem cell (mESC) self-renewal.
Read more: Additional Product Information
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More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | N.A. |
| MFCD | N.A. |
| Short Description | Stem cell inhibitor set |
References
- Q.L. Ying et al. The ground state of embryonic stem cell self-renewal. Nature, 2008, 453, 519-523.
- P. Li et al. Germline competent embryonic stem cells derived from rat blastocysts. Cell. 2008, 135, 1299-1310.
- H. Kiyonari et al. Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline‐competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability. Genesis. 2010, 48, 317-327.
- List of publications using PD184352 (Axon 1368) purchased from Axon Medchem
- List of publications using CHIR99021 (Axon 1386) purchased from Axon Medchem
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