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JNJ-42756493
- Erdafitinib
- Soluble in DMSO
- MF: C25H30N6O2
- MW: 446.55
Description
JNJ-42756493 is a potent and selective pan-FGFR inhibitor with IC50 values of 1.2, 2.5, 3.0, and 5.7 nM for FGFR1-4, respectively.
More Information
| Parent CAS No. | 1346242-81-6 |
|---|---|
| Chemical Name | 1-((3,5-Dimethoxyphenyl)(3-(1-methyl-4-pyrazolyl)-6-quinoxalinyl)amino)-2-(isopropylamino)ethane |
| SMILES | N1=C2C=CC(N(CCNC(C)C)C3=CC(OC)=CC(OC)=C3)=CC2=NC(C2C=NN(C)C=2)=C1 |
| MFCD | MFCD28502040 |
| InChi | InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3 |
| InChiKey | OLAHOMJCDNXHFI-UHFFFAOYSA-N |
| CID | 67462786 |
| Short Description | FGFR inhibitor |
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