Bulk Inquiry
Stem Cell 5i inhibitor Set
Set of 5 Inhibitors
LDN 193189 (Axon 1509)
SB 431542 (Axon 1661)
CHIR99021 (Axon 1386)
SU 5402 (Axon 1667)
DAPT (Axon 1484)
(2 mg or 5 mg of each inhibitor)
* Five Inhibitors are in powder form (high purity: 99%)
Ready to be reconstituted freshly
to their 10 mM solutions in DMSO respectively.
Expert Recommendation!
Description
A convenient set of five small molecule pathway inhibitors, BMP inhibitor LDN193189 hydrochloride (Axon 1509), TGF-beta inhibitor SB431542 (Axon 1661) and GSK-3 inhibitor CHIR99021 (Axon 1386), FGFR inhibitor SU5402 (Axon 1667) and Gamma secretase inhibitor DAPT (Axon 1484) (termed as stem cell 5i or LSB3i or LSB+3i inhibitor set), for neural differentiation of human pluripotent stem cells (hPSCs). Stem Cell 5i (or LSB3i) inhibitor cocktail protocol, actually a combination of LSB inhibitor set (Axon 5004) and neuronal 3i (CSD) inhibitor set (Axon 5006), was used for rapid and efficient differentiateing hPSCs into nociceptors.
Read more: Additional Product Information
Show all Axon Ligand™ Sets
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | N.A. |
| MFCD | N.A. |
| Short Description | Stem cell inhibitor set |
References
- S.M. Chambers et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnol. 2012, 30, 715-720.
- List of publications using LDN193189 HCl (Axon 1509) purchased from Axon Medchem
- List of publications using CHIR99021 (Axon 1386) purchased from Axon Medchem
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1386 | CHIR99021 |
From $66.00 |
| 1484 | DAPT |
From $99.00 |
| 1509 | LDN 193189 hydrochloride |
From $71.50 |
| 1661 | SB 431542 |
From $77.00 |
| 1667 | SU 5402 |
From $66.00 |
| 2128 | Stem Cell 2i inhibitor Set |
From $99.00 |
| 2129 | Stem Cell 3i inhibitor Set |
From $143.00 |
| 2130 | Stem Cell Alternative 2i inhibitor Set |
From $110.00 |
| 2837 | BMS 605541 |
From $99.00 |
| 2849 | Apatinib |
From $132.00 |
| 2865 | NVP-ACC789 |
From $99.00 |
| 2903 | SJ000291942 |
From $104.50 |
| 2930 | Alofanib |
From $99.00 |
| 2931 | BRD0705 |
From $231.00 |
| 2943 | SRI-011381 hydrochloride |
From $137.50 |
| 2951 | XL 388 |
From $137.50 |
| 2953 | Roblitinib |
From $137.50 |
| 3153 | BRD5648 |
From $198.00 |
| 3154 | rac-BRD0705 |
From $132.00 |
| 3404 | LY-364947 |
From $99.00 |
| 3552 | LDN 212854 |
From $121.00 |
| 3579 | Tideglusib |
From $66.00 |
| 3624 | Toceranib phosphate |
From $66.00 |
| 3628 | MHY-1685 |
From $55.00 |
