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SSR 128129E
- Parent CAS: 848463-13-8
- Soluble in water and DMSO
- MF: C18H15N2NaO4
- MW: 346.31
Description
More Information
| Parent CAS No. | 848463-13-8 |
|---|---|
| Chemical Name | sodium 2-amino-5-(1-methoxy-2-methylindolizine-3-carbonyl)benzoate |
| SMILES | [Na+].C([O-])(=O)C1=CC(C(C2N3C(=C(OC)C=2C)C=CC=C3)=O)=CC=C1N |
| MFCD | N.A. |
| InChi | InChI=1S/C18H16N2O4.Na/c1-10-15(20-8-4-3-5-14(20)17(10)24-2)16(21)11-6-7-13(19)12(9-11)18(22)23;/h3-9H,19H2,1-2H3,(H,22,23);/q;+1/p-1 |
| InChiKey | JFBMSTWZURKQOC-UHFFFAOYSA-M |
| CID | 68853159 |
| Short Description | FGFR inhibitor |
References
- C. Herbert et al. Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell. 2013, 23, 489-501.
- F. Bono et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013, 23, 477-488.
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