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Dofetilide
- UK 68798
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C19H27N3O5S2
- MW: 441.56
Description
More Information
| Parent CAS No. | 115256-11-6 |
|---|---|
| Chemical Name | N-(4-(2-(methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide |
| extra_info | . |
| SMILES | CS(NC1=CC=C(CCN(C)CCOC2=CC=C(NS(C)(=O)=O)C=C2)C=C1)(=O)=O |
| MFCD | MFCD00869707 |
| InChi | InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3 |
| InChiKey | IXTMWRCNAAVVAI-UHFFFAOYSA-N |
| CID | 71329 |
| Short Description | Kv11.1 channel blocker |
References
- M Gwilt et al. UK-68,798: a novel, potent and highly selective class III antiarrhythmic agent which blocks potassium channels in cardiac cells. J. Pharmacol. Expe. Ther. 1991, 256(1), 318-324.
- C Torp-Pedersen et al. Dofetilide in patients with congestive heart failure and left ventricular dysfunction. N. Engl. J. Med. 1999, 341(12), 857-865.
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