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NVP-ACC789
- ACC789 - ZK 202650
- Soluble in DMSO
- MF: C21H17BrN4
- MW: 405.29
Description
NVP-ACC789 is a VEGFR2 inhibitor (IC50 value of 0.02 µM) moderately active against VEGFR1 and VEGFR3, but has little activity against PDGFR-β tyrosine kinases. Blocks angiogenesis induced by VEGF in vivo and in vitro.
More Information
| Parent CAS No. | 300842-64-2 |
|---|---|
| Chemical Name | N-(3-Bromo-4-methylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine |
| SMILES | C1C=C(CC2=NN=C(NC3C=CC(C)=C(Br)C=3)C3=CC=CC=C23)C=CN=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C21H17BrN4/c1-14-6-7-16(13-19(14)22)24-21-18-5-3-2-4-17(18)20(25-26-21)12-15-8-10-23-11-9-15/h2-11,13H,12H2,1H3,(H,24,26) |
| InChiKey | GXWKSXUPEFVUOO-UHFFFAOYSA-N |
| CID | 6918616 |
| Short Description | VEGFR2 inhibitor |
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