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Vatalanib
- PTK 787
- Soluble in DMSO
- MF: C20H15ClN4
- MW: 346.81
Description
More Information
| Parent CAS No. | 212141-54-3 |
|---|---|
| Chemical Name | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine |
| SMILES | C1C=C2C(NC3C=CC(Cl)=CC=3)=NN=C(CC3C=CN=CC=3)C2=CC=1 |
| MFCD | MFCD08458963 |
| InChi | InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) |
| InChiKey | YCOYDOIWSSHVCK-UHFFFAOYSA-N |
| CID | 151194 |
| Short Description | VEGFR inhibitor |
References
- JM Wood et al. PTK787/ZK 222584, a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases (...). Cancer Res. 2000, 60, 2178-2189.
- EN Scott et al. Vatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours. Expert Opin Investig Drugs 2007, 16(3), 367–379.
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