BRD 73954

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2471

CAS [1440209-96-0]

MF C16H16N2O3
MW 284.31

  • Purity: 99%
  • Soluble in DMSO

BRD 73954


First dual HDAC 6/8 inhibitor (IC50 values 9000 nM, >33000 nM, 36 nM, and 120 nM for HDAC2, 4, 6, and 8. respectively) with excellent selectivity over the other class I and II HDACs tested (75- and 130-fold less potent for the next closest isoforms). Simultaneous inhibition of HDAC6 and HDAC8 has many potential therapeutic applications, providing a larger therapeutic window than inhibition of HDAC1–3.

Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €255.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €120.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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