LW 479

Based on 26 reference(s) in Google Scholar 10 10 26

Axon 2430

CAS [1688677-89-5]

MF C21H23BrN2O4S
MW 479.39

  • Purity: 98%
  • Soluble in DMSO

LW 479


HDAC inhibitor that shows marked cytotoxicity and induces apoptosis as well as cell cycle arrest in a panel of breast cancer cell lines. LW479 silences EGFR expression in breast cancer cells through disrupting Sp1 and HDAC1 binding to EGFR promoter, and blocks EGF/EGFR signalling pathway and EGF-stimulated motility. Moreover, LW-479 attenuates breast cancer metastasis to the lung.
Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €485.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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