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Axon 2155
CAS [869802-58-4]
MF C17H21N5OSMW 343.45
Potent and selective non-competitive mGlu1 receptor antagonist (IC50: 10 nM); showing 34-fold selectivity over mGluR5 and no significant activity at other mGluR receptors, neurotransmitter receptors, ion channels, and transporters. A 841720 demonstrated full efficacy in various in vivo animal pain models.
KEYWORDS: A 841720 | supplier | mGluR1 antagonist | A841720 | A-841720 | CAS [869802-58-4] | Metabotropic | Glutamate | mGluR1 | mGlu1 | Antagonist | Receptors
9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
[869802-58-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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