PH 797804

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1837

CAS [586379-66-0]

MF C22H19BrF2N2O3
MW 477.30

  • Purity: 99%
  • Soluble in DMSO and ethanol

PH 797804

Description

Highly potent, selective and metabolically stable inhibitor of p38 MAPK (p38α cascade IC50: 2.3 nM); an ATP-competitive, readily reversible inhibitor of the α isoform of human p38 MAP kinase, exhibiting a Ki of 5.8 nM; clinical candidate.

*PH 797804 is an (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer. Be careful that racemate of PH 797804 is wrongly provided by other supplier as drug PH 797804 itself. The less potent (+)-rotating atropisomer is also available (inquire). Be right about your drug.

The racemate, (±)-PH797804 (Axon 2786) is also available.

KEYWORDS: PH 797804 | supplier | p38 MAPK inhibitor | PH797804 | CAS [586379-66-0] | MAPK | MAPK (p38) | Inhibitor | Enzymes

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2 mg €115.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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