Your cart

There are no items in your shopping cart

BIX 02189

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1809

CAS [1094614-85-3]

MF C27H28N4O2
MW 440.54

  • Purity: 99%
  • Soluble in DMSO

BIX 02189

Description

Selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively.

BIX02189 is a close analogue of BIX02188-Me (Axon 1808) and BIX02188 (Axon 3346).

KEYWORDS: BIX02189 | supplier | MEK5/ERK5 inhibitor | BIX 02189 | BIX-02189 | CAS [1094614-85-3] | 1265916-41-3 (Z-isomer) | MAPK | MEK | ERK | Inhibitor | Enzymes

Order
Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
1122 SL 327 MEK1 and MEK2 inhibitor €80.00
1223 PD98059 MEK inhibitor €80.00
1357 SD 169 MAPK inhibitor (p38α specific) €60.00
1358 BIRB 796 MAPK inhibitor (p38 specific) €65.00
1363 SB 203580 MAPK inhibitor (p38 specific) €95.00
1364 SB 202190 MAPK inhibitor (p38 specific) €95.00
1365 PD169316 MAPK inhibitor (p38 specific) €95.00
1368 PD184352 MEK 1 inhibitor €80.00
1408 PD0325901 MEK1 and MEK2 inhibitor €50.00
1465 SB 203580 hydrochloride MAPK inhibitor (p38 specific) €70.00
1516 AZD6244 MEK1 and MEK2 inhibitor €60.00
1671 SCIO 469 MAPK inhibitor (p38 specific) €120.00
1694 FR 180204 ERK inhibitor; AP-1 inhibitor €95.00
1761 GSK 1120212 MEK1 and MEK2 inhibitor €70.00
1811 VX 745 Inhibitor of p38α MAP kinase €90.00
1837 PH 797804 Inhibitor of p38α MAPK €115.00
1846 XMD 8-92 BMK1 inhibitor; ERK5 inhibitor €70.00
1895 LY 2228820 Inhibitor of p38 MAPK €105.00
1999 AZD8330 MEK 1 inhibitor €105.00
1808 BIX02188-Me MEK5 inhibitor; ERK5 inhibitor €110.00
2366 NG 25 trihydrochloride Type II inhibitor of TAK1 (MAP3K7) and MAP4K2 (GCK) €75.00
2438 Cuspin-1 Upregulator of the Survival of Motor Neuron protein (SMN) by Ras signaling activation €95.00
2444 SB 706504 Selective p38 MAPK inhibitor that targets a subset of inflammatory macrophage genes. €125.00
2520 U 0126 Non-competitive inhibitor of MEK1/2 and protects brain in stroke models €90.00
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
3059 GW 284543 hydrochloride Selective MEK5 inhibitor €95.00
3346 BIX02188 Potent MEK5 inhibitor €110.00
1621 XMD 8-92 trifluoroacetate BMK1 inhibitor; ERK5 inhibitor €70.00
3697 Binimetinib Potent, selective, non-ATP-competitive and orally available allosteric inhibitor of MEK1/2 €60.00
3741 GDC-0994 ERK1/2 inhibitor Inquire
3803 SCH900353 ERK1/2 inhibitor Inquire
3836 VX-11e Potent, selective, and orally bioavailable inhibitor of ERK2 Inquire
3874 RDEA119 Potent and highly selective small molecule allosteric MEK inhibitor Inquire
4148 GDC-0973 Orally bioavailable, potent and selective small-molecule inhibitor of mitogen-activated protein kinase 1 Inquire
4151 Ulixertinib hydrochloride Potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases Inquire
4217 AS-703026 Potent, selective and orally bioavailable small molecular inhibitor of MEK1/2 Inquire

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...