HMR 1098 - HMR 1883 sodium salt

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1757

CAS [261717-22-0]

MF C19H21ClN3NaO5S2
MW 493.96

Purity: 98%
Soluble in water and DMSO

HMR 1098

Description

KATP channel blocker; HMR 1098 acts by inactivating the ATP-sensitive potassium channels (KATP) responsible for potassium efflux. HMR 1098 is an inhibitor of Kir6.2/SUR1-composed K(ATP) channels

H Gögelein et al. Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion. N. Schmiedebergs Arch Pharmacol. 2001, 364(1), 33-41.

HX ZHang et al. HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels. J. Mol. Cell Cardiol. 2011, 50(3), 552-560.

K+ channel blocker (SUR1/Kir6.2 selective)

Chemical name

sodium (5-chloro-2-methoxybenzoyl)(4-methoxy-3-(N-(methylcarbamothioyl)sulfamoyl)phenethyl)amide

Parent CAS No.

[158751-64-5]

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HMR 1098 - HMR 1883 sodium salt

Description

Chemical name

Parent CAS No.

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HMR 1098 - HMR 1883 sodium salt

Description

Chemical name

Parent CAS No.

Related Products

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