XMD 8-92 trifluoroacetate

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1621

CAS [1234480-50-2]

MF C26H30N6O3.C2HF3O2
MW 588.58

  • Purity: 99%
  • Soluble in water and DMSO

XMD 8-92 trifluoroacetate


Potent and selective inhibitor of big MAP kinase 1 (BMK1/ERK5).

Note: Free base form of XMD 8-92 (Axon 1846) is also available

BMK1 inhibitor; ERK5 inhibitor

Chemical name

2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 2,2,2-trifluoroacetate

Source information

Sold under agreement with the Dana-Faber Cancer Institute

Parent CAS No.


Size Unit Price Stock
2 mg €70.00 In Stock
5 mg €95.00 In Stock
25 mg €295.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €460.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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