Bulk Inquiry
AZD6244
- Selumetinib - ARRY 142886
- Soluble in DMSO
- MF: C17H15BrClFN4O3
- MW: 457.68
Description
More Information
| Parent CAS No. | 606143-52-6 |
|---|---|
| Chemical Name | 5-(4-bromo-2-chlorophenylamino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide |
| SMILES | C1C(C(=O)NOCCO)=C(NC2C(Cl)=CC(Br)=CC=2)C(F)=C2N=CN(C)C=12 |
| MFCD | MFCD11977472 |
| InChi | InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26) |
| InChiKey | CYOHGALHFOKKQC-UHFFFAOYSA-N |
| CID | 10127622 |
| Short Description | MEK inhibitor |
References
- TC Yeh et al. Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor. Clin. Cancer Res. 2007, 13, 1576-1583.
- BR Davies et al. AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases. Mol. Cancer Ther. 2007, 6(8), 2209-2019.
- List of publications using AZD6244 (Axon 1516) purchased from Axon Medchem
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1122 | SL 327 |
From $88.00 |
| 1223 | PD98059 |
From $88.00 |
| 1357 | SD 169 |
From $66.00 |
| 1358 | BIRB 796 |
From $71.50 |
| 1363 | SB 203580 |
From $104.50 |
| 1364 | SB 202190 |
From $104.50 |
| 1365 | PD169316 |
From $104.50 |
| 1368 | PD184352 |
From $88.00 |
| 1408 | PD0325901 |
From $55.00 |
| 1465 | SB 203580 hydrochloride |
From $77.00 |
| 1621 | XMD 8-92 trifluoroacetate |
From $77.00 |
| 1671 | SCIO 469 |
From $132.00 |
| 1694 | FR 180204 |
From $104.50 |
| 1761 | GSK 1120212 |
From $77.00 |
| 1808 | BIX02188-Me |
From $121.00 |
| 1809 | BIX 02189 |
From $121.00 |
| 1811 | VX 745 |
From $99.00 |
| 1837 | PH 797804 |
From $126.50 |
| 1846 | XMD 8-92 |
From $77.00 |
| 1895 | LY 2228820 |
From $115.50 |
| 1999 | AZD8330 |
From $115.50 |
| 2366 | NG 25 trihydrochloride |
From $82.50 |
| 2444 | SB 706504 |
From $137.50 |
| 2520 | U 0126 |
From $99.00 |
