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B-HT 920 dihydrochloride
- Talipexole
Axon 1153
- Parent CAS: 101626-70-4
Purity:
99%
- Soluble in water and DMSO
- MF: C10H15N3S.2HCl
- MW: 282.23
Description
Dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist.
More Information
| Parent CAS No. | 101626-70-4 |
|---|---|
| Chemical Name | 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-ylamine dihydrochloride |
| SMILES | C12N=C(SC=1CCN(CC=C)CC2)N.Cl.Cl |
| MFCD | MFCD00274573 |
| InChi | InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H |
| InChiKey | DPQAXNSOFFYKDS-UHFFFAOYSA-N |
| CID | 104870 |
| Short Description | α2 and D2 agonist |
References
- GS Robertson et al. In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release. J. Pharmacol. Exp. Ther. 1993, 264, 1344.
- H Nishio et al. 5-HT3 receptor blocking properties of the antiParkinsonian agent, talipexole. Gen. Pharmacol. 1996, 27(5), 779-785.
- G Cichini et al. B-HT 920 and B-HT 958: Presynaptic effects on electrically evoked 3H-dopamine release from slices of rat nucleus accumbens. Naunyn-Schmiedeberg's Arch. Pharmacol. 1987, 335, 28-31.
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