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SL 327
- Soluble in DMSO
- MF: C16H12F3N3S
- MW: 335.35
Description
More Information
| Parent CAS No. | 305350-87-2 |
|---|---|
| Chemical Name | E/Z-α-[amino[(4-aminophenyl)thio]methylen]-2-(trifluoromethyl)benzeneacetonitrile |
| SMILES | C1C=C(SC(N)=C(C#N)C2C(C(F)(F)F)=CC=CC=2)C=CC=1N |
| MFCD | MFCD06411432 |
| InChi | InChI=1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2 |
| InChiKey | JLOXTZFYJNCPIS-UHFFFAOYSA-N |
| CID | 9549284 |
| Short Description | MEK inhibitor |
References
- X Wang et al. Significant neuroprotection against ischemic brain injury of inhibition of MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J. Pharmacol. Exp. Ther. 2003, 304, 172-178.
- R Longoni et al. The MEK inhibitor SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: a behavioral and immunohistochemical study. Psychopharmacology (Berl). 2011, 216(1), 63-73.
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