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CP 775146

Axon 2114
CAS:  702680-17-9
  • Optical Purity:  Optically pure
  • Soluble in DMSO
  • MF:  C26H33NO4
  • MW:  423.54

Description

Potent and selective PPARα agonist (Ki=24.5 nM and >10 µM for PPARβ and PPARγ), supporting robust recruitment of co-activator peptides in vitro. CP775146 markedly potentiates chimeric transcription systems in cell-based assays and strikingly lowers serum triglycerides in vivo

More Information

Parent CAS No. 702680-17-9
Chemical Name (S)-2-(3-(1-(2-(4-isopropylphenyl)acetyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid
extra_info .
SMILES C(O)(=O)C(C)(OC1=CC=CC([C@@H]2CCCN(C(CC3=CC=C(C(C)C)C=C3)=O)C2)=C1)C |&1:11,r|
MFCD N.A.
InChi InChI=1S/C26H33NO4/c1-18(2)20-12-10-19(11-13-20)15-24(28)27-14-6-8-22(17-27)21-7-5-9-23(16-21)31-26(3,4)25(29)30/h5,7,9-13,16,18,22H,6,8,14-15,17H2,1-4H3,(H,29,30)/t22-/m1/s1
InChiKey OISHBINQIFNIPV-JOCHJYFZSA-N
CID 10410059
Short Description PPARα agonist

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