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VU 0364439
- Soluble in DMSO
- MF: C18H13Cl2N3O3S
- MW: 422.29
Description
More Information
| Parent CAS No. | 1246086-78-1 |
|---|---|
| Chemical Name | N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide |
| SMILES | C1(C(NC2=CC=C(S(NC3=CC=CC=C3Cl)(=O)=O)C(Cl)=C2)=O)=NC=CC=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24) |
| InChiKey | IXHCGJXBIHHIEF-UHFFFAOYSA-N |
| CID | 46934289 |
| Short Description | mGLuR4 PAM |
References
- DW Engers et al. Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS). Bioorg. Med. Chem. Lett. 2010, 20(17), 5175-5178.
- AJ Robichaud et al. Recent Progress on the Identification of Metabotropic Glutamate 4 Receptor Ligands and Their Potential Utility as CNS Therapeutics. ACS Chem. Neurosci. 2011, 2(8), 433–449.
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