Naive Stem Cell 5i inhibitor Set

Based on 14 reference(s) in Google Scholar 10 10 14

Axon 5011

CAS [N.A.]

MF #N/A
MW #N/A

  • Purity: 99%
  • Soluble in DMSO

Naive Stem Cell 5i inhibitor Set

Description

A convenient set of five small molecule pathway inhibitors (termed as Naive stem cell 5i inhibitors): - BRAF inhibitor SB 590885 (Axon 2504) - MEK inhibitor PD 0325901 (Axon 1408) - ROCK inhibitor Y 27632 dihydrochloride (Axon 1683) - SRC/LCK inhibitor WH 4-023 (Axon 2381) - GSK3β inhibitor IM-12 (Axon 2511).
(*Alternatively, CHIR99021 (Axon 1386) can be used as GSK3β inhibitor. Not included.)
The combination of five inhibitors of MEK, GSK3β, BRAF, ROCK, and SRC, supports the expansion of viable OCT4-ΔPE-GFP+ human pluripotent cells after exogenous transcription factor expression has been removed. Useful tool for the induction and maintenance of human naive stem cell pluripotency.

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KEYWORDS: Naive Stem Cell 5i inhibitor Set | supplier | Stem cell inhibitor set | SB 590885 | PD 0325901 | Y 27632 | WH-4-023 | IM 12 | CAS [405554-55-4] | [391210-10-9] | [129830-38-2] | [837422-57-8] | [1129669-05-1] | Inhibitor | Axon Ligand Sets | BRAF | MEK | ROCK | Src | Lck | GSK3β | naive | expansion | OCT4-ΔPE-GFP+ | pluripotent | hPCs | transcription factor | induction | human | stem cell | hPSC | pluripotency

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Size Unit Price Stock
Each 2 mg €240.00 In Stock
Each 5 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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