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WH-4-023

Axon 2381
CAS:  837422-57-8
Purity:  99%
  • Soluble in DMSO
  • MF:  C32H36N6O4
  • MW:  568.67

Description

Orally active inhibitor of Lck and Src (IC50 values 2 nM and 6 nM for Lck and Src, respectively) with an >300-fold selectivity over p38α and KDR.

*Promotion: WH-4-023 is an important componant of Inhibitor Set(s):

Naive Stem Cell 5i inhibitor Set (Axon 5011)

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 837422-57-8
Chemical Name 2,6-dimethylphenyl 2,4-dimethoxyphenyl(2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)carbamate
SMILES C(OC1=C(C)C=CC=C1C)(=O)N(C1=CC=C(OC)C=C1OC)C1C=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2)N=1
MFCD N.A.
InChi InChI=1S/C32H36N6O4/c1-22-7-6-8-23(2)30(22)42-32(39)38(27-14-13-26(40-4)21-28(27)41-5)29-15-16-33-31(35-29)34-24-9-11-25(12-10-24)37-19-17-36(3)18-20-37/h6-16,21H,17-20H2,1-5H3,(H,33,34,35)
InChiKey NBTNHSGBRGTFJS-UHFFFAOYSA-N
CID 11844351
Short Description Lck/Src inhibitor

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