Bulk Inquiry
WH-4-023
- Soluble in DMSO
- MF: C32H36N6O4
- MW: 568.67
Description
Orally active inhibitor of Lck and Src (IC50 values 2 nM and 6 nM for Lck and Src, respectively) with an >300-fold selectivity over p38α and KDR.
*Promotion: WH-4-023 is an important componant of Inhibitor Set(s):
| Naive Stem Cell 5i inhibitor Set (Axon 5011) |
More Information
| Parent CAS No. | 837422-57-8 |
|---|---|
| Chemical Name | 2,6-dimethylphenyl 2,4-dimethoxyphenyl(2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)carbamate |
| SMILES | C(OC1=C(C)C=CC=C1C)(=O)N(C1=CC=C(OC)C=C1OC)C1C=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2)N=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C32H36N6O4/c1-22-7-6-8-23(2)30(22)42-32(39)38(27-14-13-26(40-4)21-28(27)41-5)29-15-16-33-31(35-29)34-24-9-11-25(12-10-24)37-19-17-36(3)18-20-37/h6-16,21H,17-20H2,1-5H3,(H,33,34,35) |
| InChiKey | NBTNHSGBRGTFJS-UHFFFAOYSA-N |
| CID | 11844351 |
| Short Description | Lck/Src inhibitor |
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