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J147
- Soluble in DMSO
- MF: C18H17F3N2O2
- MW: 350.33
Description
J147 is a potent and orally active neurotrophic drug that facilitates memory in normal rodents. Moreover, J147 prevents the loss of synaptic proteins and cognitive decline in a transgenic AD mouse model. Neuroprotectant.
More Information
| Parent CAS No. | 1146963-51-0 |
|---|---|
| Chemical Name | N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-(3-methoxybenzylidene)acetohydrazide |
| SMILES | C1C=C(/C=N/N(C(C(F)(F)F)=O)C2C=CC(C)=CC=2C)C=C(OC)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+ |
| InChiKey | HYMZAYGFKNNHDN-SSDVNMTOSA-N |
| CID | 25229652 |
| Short Description | Neurotrophic drug |
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