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FC 99 hydrochloride

Axon 2318
  • Parent CAS:  1097810-71-3
Purity:  98%
  • Soluble in water and DMSO
  • MF:  C15H18N2O.HCl
  • MW:  304.3

Description

Inhibitor of TLR3 expression and inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. FC-99 suppressed the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein The ability of FC-99 to reverse TLR3 expression may account for its marked effect on the model of sepsis.

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 1097810-71-3
Chemical Name N1-(4-methoxybenzyl)-4-methylbenzene-1,2-diamine hydrochloride (1:1)
SMILES C1(OC)C=CC(CNC2C(N)=CC(C)=CC=2)=CC=1.Cl
MFCD N.A.
InChi InChI=1S/C15H18N2O.ClH/c1-11-3-8-15(14(16)9-11)17-10-12-4-6-13(18-2)7-5-12;/h3-9,17H,10,16H2,1-2H3;1H
InChiKey BBJOTJUVSXQGPN-UHFFFAOYSA-N
CID 91826509
Short Description TLR3 suppressor

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