FC 99 hydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2318

CAS [N.A.]

MF C15H18N2O.xHCl
MW 304,30

  • Purity: 98%
  • Soluble in water and DMSO

FC 99 hydrochloride

Description

Inhibitor of TLR3 expression and inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. FC-99 suppressed the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein The ability of FC-99 to reverse TLR3 expression may account for its marked effect on the model of sepsis.
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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