ATB 346

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2288

CAS [1226895-20-0]

MW 365.45

  • Purity: 99%
  • Soluble in DMSO

ATB 346


Orally active hydrogen sulfide-releasing cyclooxygenase inhibitor and a derivative of Naproxen (significantly reduced exudate leukocyte and PGE2 levels at 30 µmol/kg oral administration). ATB-346 exhibits anti-inflammatory properties similar to naproxen.In a mouse airpouch model, ATB-346 suppressed cyclooxygenase-2 activity and inhibited leukocyte infiltration more effectively than naproxen but with substantially reduced gastrointestinal toxicity (100-fold safer than naproxen).

KEYWORDS: ATB 346 | supplier | COX inhibitor; H2S-releasing compound | ATB346 | CAS [1226895-20-0] | Fatty acid (Arachidonic acid) | COX | Inhibitor | cyclooxygenase | Naproxen | anti-inflammatory | leukocyte infiltration

Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €410.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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