SCH 529074

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2244

CAS [922150-11-6]

MF C31H36Cl2N6
MW 563.56

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

SCH 529074

Description

Small molecule activator of mutant p53 which binds p53 DNA binding domain (DBD; Kd value 1-2 μM). SCH 529074 restores growth-suppressive function to mutant p53 (R273H and the structural mutant R249S) by acting as a chaperone and interrupts HDM2-mediated ubiquitination of wild type p53.
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5 mg €100.00 In Stock
25 mg €380.00 In Stock
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2 x 5 mg €160.00 In Stock
2 x 25 mg €620.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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