AST 1306 tosylate

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1986

CAS [1050500-29-2]

MF C24H18ClFN4O2.C7H8O3S
MW 621.08

  • Purity: 98%
  • Soluble in DMSO

AST 1306 tosylate

Description

A selective, irreversible ErbB2 and EGFR inhibitor whose growth-inhibitory effects are more potent in ErbB2-overexpressing cells; AST1306 potently inhibits wild-type EGFR and ErbB2, as well as EGFR mutant T790M/L858R, in both cell-free and intact cell assays; IC50 values to be 0.5, 3.0, 0.8 and 12 nM for EGFR, ErbB2, ErbB4 and EGFR mutant T790M/L858R, respectively
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5 mg €105.00 In Stock
25 mg €365.00 In Stock
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2 x 5 mg €160.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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