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(R)-(+)-BAY K 8644
- (+)-BAY K8644- Optical Purity: 99% e.e.
- Soluble in DMSO and EtOH
- MF: C16H15F3N2O4
- MW: 356.3
Description
More Information
| Parent CAS No. | 98791-67-4 |
|---|---|
| Chemical Name | (R)-methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate |
| SMILES | C1C=CC=C([C@@H]2C(C(OC)=O)=C(C)NC(C)=C2[N+]([O-])=O)C=1C(F)(F)F |&1:5,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m1/s1 |
| InChiKey | ZFLWDHHVRRZMEI-CYBMUJFWSA-N |
| CID | 6604881 |
| Short Description | Calcium (Ca2+) channel activator |
References
- FT Van Amsterdam et al. Stereoisomers of Bay K 8644 show opposite activities in the normal and ischemic rat heart. A comparison with nifedipine. Naunyn Schmiedebergs Arch. Pharmacol. 1989, 339, 647-652.
- U Ravens et al. Opposite cardiac actions of the enantiomers of Bay K 8644 at different membrane potentials in guinea-pig papillary muscles. Naunyn Schmiedebergs Arch. Pharmacol. 1990, 341, 232-239.
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