Calcium channels have long been the target of therapeutic drugs aimed at treating the symptoms of cardiovascular disease and migraine headache. They regulate the permeability of the cell membrane towards calcium. Axon Medchem offers pharmacological standards that interact at each of the 2 main classes within the family of calcium channels, the voltage-gated, and the ligand-gated channels.[1].

[1] InternationalUnion of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels. WA Catterall, E Perez-Reyes, TP Snutch, J Striessnig. Pharmacol Rev 57:411–425, 2005

13 Item(s)

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Axon ID Name Description From price
3015 Amlodipine besylate Ca2+ channel blocker €90.00
3013 Aranidipine Ca2+ channel antagonist €110.00
3014 Barnidipine hydrochloride Potent Ca2+ channel blocker (L-type voltage gated) €105.00
1697 BAY K 8644 Calcium (Ca2+) channel activator (L-type voltage-gated) €95.00
1758 BAY K 8644, (R)-(+)- Calcium (Ca2+) channel modulator €115.00
1759 BAY K 8644, (S)-(-)- Calcium (Ca2+) channel activator (L-type voltage-gated) €115.00
1868 CRAC inhibitor 44 Potent and selective CRAC ion channel blocker €110.00
2952 Fantofarone Highly potent and specific Ca2+ channel antagonist €125.00
1448 Felodipine Ca2+ channel blocker €65.00
2068 Nifedipine Ca2+ channel blocker (L-type voltage gated) €55.00
1823 Pregabalin Reduces synaptic signaling by binding to α2δ subunits €85.00
1221 SKF 96365 hydrochloride Ca2+ channel blocker €105.00
3025 Z944 Highly selective, orally available Ca2+ channel blocker (T-type voltage gated)  Recently added €125.00

13 Item(s)

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