Calcium
Calcium channels have long been the target of therapeutic drugs aimed at treating the symptoms of cardiovascular disease and migraine headache. They regulate the permeability of the cell membrane towards calcium. Axon Medchem offers pharmacological standards that interact at each of the 2 main classes within the family of calcium channels, the voltage-gated, and the ligand-gated channels.[1].
[1] InternationalUnion of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels. WA Catterall, E Perez-Reyes, TP Snutch, J Striessnig. Pharmacol Rev 57:411–425, 2005
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3015 | Amlodipine besylate | Ca2+ channel blocker | €90.00 | |
| 3013 | Aranidipine | Ca2+ channel antagonist | €110.00 | |
| 3160 | Azelnidipine | Calcium channel blocker | Recently added | €70.00 |
| 3014 | Barnidipine hydrochloride | Potent Ca2+ channel blocker (L-type voltage gated) | €105.00 | |
| 1697 | BAY K 8644 | Calcium (Ca2+) channel activator (L-type voltage-gated) | €95.00 | |
| 1758 | BAY K 8644, (R)-(+)- | Calcium (Ca2+) channel modulator | €115.00 | |
| 1759 | BAY K 8644, (S)-(-)- | Calcium (Ca2+) channel activator (L-type voltage-gated) | €115.00 | |
| 3131 | Benidipine hydrochloride | Ca2+ channel blocker | €70.00 | |
| 1868 | CRAC inhibitor 44 | Potent and selective CRAC ion channel blocker | €110.00 | |
| 2952 | Fantofarone | Highly potent and specific Ca2+ channel antagonist | €125.00 | |
| 1448 | Felodipine | Ca2+ channel blocker | €65.00 | |
| 3185 | L651582 | Ca2+ channel blocker | Recently added | €120.00 |
| 2068 | Nifedipine | Ca2+ channel blocker (L-type voltage gated) | €55.00 | |
| 3158 | Otilonium bromide | Ca2+ channel blocker | Recently added | €70.00 |
| 1823 | Pregabalin | Reduces synaptic signaling by binding to α2δ subunits | €85.00 | |