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Aranidipine
- MPC-1304 - Sapresta
- Soluble in DMSO
- MF: C19H20N2O7
- MW: 388.37
Description
Calcium antagonist with potent and long-lasting vasodilating and antihypertensive activities.
More Information
| Parent CAS No. | 86780-90-7 |
|---|---|
| Chemical Name | 3-Methyl 5-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| SMILES | C1(C(=O)OC)C(C2C=CC=CC=2[N+]([O-])=O)C(C(=O)OCC(=O)C)=C(C)NC=1C |
| MFCD | MFCD00865813 |
| InChi | InChI=1S/C19H20N2O7/c1-10(22)9-28-19(24)16-12(3)20-11(2)15(18(23)27-4)17(16)13-7-5-6-8-14(13)21(25)26/h5-8,17,20H,9H2,1-4H3 |
| InChiKey | NCUCGYYHUFIYNU-UHFFFAOYSA-N |
| CID | 2225 |
| Short Description | Ca channel antagonist |
References
- A Kanda et al. Cardiovascular profile of MPC-1304, a novel dihydropyridine calcium antagonist: comparison with other calcium antagonists. J Cardiovasc Pharmacol. 1993 Jul;22(1):167-75.
- K Miyoshi et al. MPC-1304, another type of dihydropyridine, possessing highly potent vasodilating action. Eur J Pharmacol. 1993 Jul 20;238(2-3):139-48.
- S Ohno et al. Synthesis of asymmetric 4-aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylates with vasodilating and antihypertensive activities. Chem Pharm Bull (Tokyo). 1986 Apr;34(4):1589-606.
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