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Barnidipine hydrochloride
- YM 09730-5 - Mepirodipine hydrochloride
- Parent CAS: 104713-75-9
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C27H29N3O6.HCl
- MW: 528
Description
Barnidipine hydrochloride is a potent calcium antagonist with a Ki value of 0.205 nM. Barnidipine hydrochloride produces its antihypertensive effect by selective blockade of calcium ion influx via the L-subtype ‘voltage-operated’ channels in the excitable membranes of vascular smooth muscle cells, as a result of interaction with specific L-type calcium channel receptors.
More Information
| Parent CAS No. | 104713-75-9 |
|---|---|
| Chemical Name | (S)-3-((S)-1-Benzylpyrrolidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride |
| SMILES | C1(C(=O)OC)[C@]([H])(C2C=CC=C([N+]([O-])=O)C=2)C(C(=O)O[C@]2([H])CN(CC3C=CC=CC=3)CC2)=C(C)NC=1C.Cl |&1:5,20,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C27H29N3O6.ClH/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19;/h4-11,14,22,25,28H,12-13,15-16H2,1-3H3;1H/t22-,25-;/m0./s1 |
| InChiKey | XEMPUKIZUCIZEY-YSCHMLPRSA-N |
| CID | 443868 |
| Short Description | Ca channel blocker |
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