ABT 869 - Linifanib

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1638

CAS [796967-16-3]

MF C21H18FN5O
MW 375.40

  • Purity: 99%
  • Soluble in DMSO

ABT 869

Description

A multi-targeted receptor tyrosine kinase (RTK) inhibitor, targeting VEGRFs, PDGFRs, Fms-like tyrosine kinase-3 and c-KIT. In cellular assays ABT869 inhibits RTK phosphorylation (IC50 = 2, 4, and 7 nM for PDGFR-β, KDR, and CSF-1R, respectively) and VEGF-stimulated proliferation (IC50 = 0.2 nM for human endothelial cells)
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Size Unit Price Stock
5 mg €85.00 In Stock
10 mg €120.00 In Stock
25 mg €250.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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