Nutlin-3

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1585

CAS [548472-68-0]

MF C30H30Cl2N4O4
MW 581.49

  • Purity: 99%
  • Soluble in DMSO and Ethanol

Nutlin-3

Description

MDM2 antagonist, which binds MDM2 in the p53-binding pocket and activates the p53 pathway in cancer cells, leading to cell cycle arrest, apoptosis, and growth inhibition of human tumor xenografts in nude mice.

Note: Its two enantiomers, more active (-)-enantiomer Nutlin-3a (Axon 1880) and less active (+)-enantiomer Nutlin-3b (Axon 1881), are also available.

Order
Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €330.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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