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CT 53518
- MLN518 - Tandutinib
- Soluble in DMSO
- MF: C31H42N6O4
- MW: 562.7
Description
More Information
| Parent CAS No. | 387867-13-2 |
|---|---|
| Chemical Name | 4-[7-(3-Piperidin-1-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide |
| SMILES | C1(OCCCN2CCCCC2)C=C2N=CN=C(N3CCN(C(NC4C=CC(OC(C)C)=CC=4)=O)CC3)C2=CC=1OC |
| MFCD | MFCD09954147 |
| InChi | InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38) |
| InChiKey | UXXQOJXBIDBUAC-UHFFFAOYSA-N |
| CID | 3038522 |
| Short Description | FLT3 inhibitor |
References
- L Kelly et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). Cancer Cell , 2003, 1(5), 421 - 432. [online abstract]
- IJ Griswold et al. Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis. Blood 2004, 104(9), 2912-8. [online abstract]
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