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Biphenyl-indanone A
- BINA - LS 193571
- Soluble in DMSO
- MF: C30H30O4
- MW: 454.56
Description
More Information
| Parent CAS No. | 866823-73-6 |
|---|---|
| Chemical Name | 3'-((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yloxy)methyl)biphenyl-4-carboxylic acid |
| SMILES | O=C1C(C2CCCC2)CC2=CC(OCC3C=CC=C(C4C=CC(C(=O)O)=CC=4)C=3)=C(C)C(C)=C12 |
| MFCD | N.A. |
| InChi | InChI=1S/C30H30O4/c1-18-19(2)28-25(15-26(29(28)31)22-7-3-4-8-22)16-27(18)34-17-20-6-5-9-24(14-20)21-10-12-23(13-11-21)30(32)33/h5-6,9-14,16,22,26H,3-4,7-8,15,17H2,1-2H3,(H,32,33) |
| InChiKey | KMKBEESNZAPKMP-UHFFFAOYSA-N |
| CID | 9868580 |
| Short Description | mGluR2 PAM |
References
- R Galici et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol. Exp. Ther. 2006, 318(1), 173–185.
- MA Benneyworth et al. A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Mol. Pharmacol. 2007, 72(2), 477–484.
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