XE 991 dihydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1305

CAS [122955-13-9]

MF C26H20N2O.2HCl
MW 449.37

Purity: 99%
Soluble in DMSO

XE 991 dihydrochloride

Description

KCNQ channel and M-current blocker; potential AD therapeutic.
The parent molecule of XE 991 (Axon 1987) is available as well.

Wang et al. KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science 1998, 282 1890.

Zaczek et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl) -9(10H)-anthracenone: comparison to linopirdine. J. Pharmacol. Exp. Ther. 1998, 285 724.

KCNQ channel and M-current blocker

Chemical name

10,10-bis(pyridin-4-ylmethyl)anthracen-9(10H)-one dihydrochloride

Parent CAS No.

[122955-42-4]

Order

Size	Unit Price	Stock
10 mg	€90.00	In Stock
50 mg	€300.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description
1112	BMS 204352	Maxi K+ channel opener	€110.00
1248	Zatebradine hydrochloride	HCN channel blocker	€110.00
1274	PNU 37883 hydrochloride	K+ channel blocker (ATP sensitive, vascular)	€85.00
1294	Chromanol 293B	KCNQ1 channel blocker	€120.00
1308	(±)-BMS 204352	Potassium channel opener; racemate of Axon 1112	Inquire
1309	(R)-(-)-BMS 204352	Potassium channel opener; Less active enantiomer of Axon 1112	€145.00
1313	1-EBIO	K+ channel opener (Ca2+ activated)	€50.00
1322	DMP 543	K+ channel blocker; Ach release stimulator	€90.00
1437	Flupirtine maleate	Analgesic	€65.00
1525	Retigabine	KCNQ channel opener; Anti-convulsant	€90.00
1647	NN 414	K+ channel opener (SUR1/Kir6.2 selective)	€110.00
1657	S 9947	Ikur/Kv1.5 channel Inhibitor	€125.00
1735	Kv1.3 Channel blocker 42	Kv1.3 potassium channel blocker	€110.00
1757	HMR 1098	K+ channel blocker (SUR1/Kir6.2 selective)	€95.00
2064	Glibenclamide potassium salt	KATP channel blocker; inhibits SUR1	€50.00
2094	NS 6180	KCa3.1 channel blocker	€90.00
2103	Dofetilide	Kv11.1 (hERG) channel blocker	€85.00
2243	AVE 0118 hydrochloride	Potassium channel blocker (Kv1.5 (IKur), Kv4.3 (Ito), Kir3.4 (IKAch), and IKr currents)	€120.00
2252	Retigabine dihydrochloride	KCNQ channel opener; Anti-convulsant	€90.00
2403	PK-THPP	Potent TASK-3 antagonist with selectivity over a wide range of potassium channels	€140.00
2329	NS 19504	Potent activator of large-conductance Ca2+-activated potassium (BK) channels	€90.00
2615	ML252	Selective and brain penetrant KCNQ2 inhibitor	€95.00
2724	ICA-069673	KCNQ2/KCNQ3 channel opener; Anti-convulsant	€90.00
2747	ML 213	KCNQ2/KCNQ4 channel opener	€75.00
3196	ML277	Potent and selective KCNQ1 channel activator	€80.00
3507	Ranolazine	Ca2+/K+/Na+ channel blocker; Anti-anginal agent	€70.00

Customer Support

Customer Services

About Axon Medchem

Contact Us

XE 991 dihydrochloride

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Customer Support

Customer Services

About Axon Medchem

Contact Us

XE 991 dihydrochloride

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us