Flupirtine maleate - D 9998 | Katadolon

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1437

CAS [75507-68-5]

MF C15H17FN4O2.C4H4O4
MW 420.39

Purity: 99%
Soluble in DMSO

Flupirtine maleate

Description

A centrally acting, nonopioid analgesic; flupirtine has a functional profile similar to NMDA-receptor antagonists, but devoid of the typical side effects of these drugs; flupirtine exerts potent cyto- and neuroprotective actions in different in vivo and in vitro models

MD Swedberg et al. Pharmacological mechanisms of action of flupirtine: a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat. J. Pharmacol. Exp. Ther. 1988, 246(3), 1067–74.

S Dhar et al. Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons. Ann. Neurol. 2002, 51 (4), 448–66.

G. Schuster et al. Flupirtine: A Review of Its Neuroprotective and Behavioral Properties. CNS Drug Reviews, 1998, 4(2), 149-164.

Analgesic

Chemical name

[2-Amino-6-(4-fluoro-benzylamino)-pyridin-3-yl]-carbamic acid ethyl ester maleate

Parent CAS No.

[56995-20-1]

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Flupirtine maleate - D 9998 | Katadolon

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Parent CAS No.

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Flupirtine maleate - D 9998 | Katadolon

Description

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Parent CAS No.

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