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Stem Cell CSD inhibitor Set

Axon 5006

Set of 3 Inhibitors
CHIR99021 (Axon 1386)
SU 5402 (Axon 1667)
DAPT (Axon 1484)
(2 mg or 5 mg of each inhibitor)

* Three Inhibitors are in powder form (high purity: 99%)
Ready to be reconstituted freshly
to their 10 mM solutions in DMSO respectively.

Expert Recommendation!

Description

A convenient set of three small molecule inhibitors, GSK-3 inhibitor CHIR99021 (Axon 1386), FGFR inhibitor SU5402 (Axon 1667) and gamma secretase inhibitor DAPT (Axon 1484) (termed as CSD or neuronal 3i). CHIR99021 is the key factor for inducing neuronal differentiation, whereas SU5402 and DAPT further enhance efficiency.

The combination of stem cell CSD (neuronal 3i) inhibitor set with LSB inhibitor set (Axon 5004) forms stem cell 5i inhibitor set (Axon 5007, aka LSB3i or LSB+3i), which was used for rapid and efficient differentiation of human pluripotent stem cells (hPSCs) into nociceptors.

Read more: Additional Product Information

Show all Axon Ligand™ Sets

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