C-82

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 3748

CAS [1422253-37-9]

MF C33H34N6O4
MW 578.66

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in DMSO
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C-82

Description

C-82 is the second-generation, potent and specific inhibitor of CBP/β-catenin complex, and a modulator of the β-catenin dependent canonical Wnt signaling pathway in cancer stem cells. C-82 is the active form that experts its effort on the designated target. It is rapidly generated (via dephosphorylation) in vivo from its pre-drug PRI-724 available as Axon 3749.

* Sold in collaboration with Chemietek.

KEYWORDS: C-82 | Supplier | Wnt/CREB inhibitor | C82 | C 82 | CT-C82 | CAS [1422253-37-9] | ECM-adhesion | β-Catenin | Wnt | Inhibitor | Proteins

Specific inhibitor of Wnt/β-catenin signaling pathway

Chemical name

(6S,9S,9aS)-N-Benzyl-6-(4-hydroxybenzyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1422253-37-9]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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