AZD7325

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3087

CAS [942437-37-8]

MF C19H19FN4O2
MW 354.38

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

AZD7325

Description

AZD7325 is a potent, selective GABAA-α2 and GABAA-α3 modulator intended for the treatment of anxiety (pKi value of 9.51 for GABAA-α2).

C Alhambra et al. Development and SAR of functionally selective allosteric modulators of GABAA receptors. Bioorg Med Chem. 2011 May 1;19(9):2927-38.

D Zhou et al. A clinical study to assess CYP1A2 and CYP3A4 induction by AZD7325, a selective GABA(A) receptor modulator - an in vitro and in vivo comparison. Br J Clin Pharmacol. 2012 Jul;74(1):98-108.

CNS GABA-A Unclassified

Potent, selective GABAA-α2 and GABAA-α3 modulator

Chemical name

4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide

Parent CAS No.

[942437-37-8]

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Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€270.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock

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AZD7325

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AZD7325

Description

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